Caffeine Extract – Central Nervous System Stimulant and Metabolic Enhancer
Caffeine Extract, a purified form of the methylxanthine alkaloid derived from natural sources such as coffee beans, tea leaves, or guarana, is a well-established central nervous system stimulant known for its neuromodulatory, thermogenic, and lipolytic properties.
Biochemically, caffeine functions primarily as a non-selective adenosine receptor antagonist, blocking A1 and A2A receptors in the brain. This inhibition results in increased release of dopamine, norepinephrine, and acetylcholine, leading to enhanced alertness, reduced fatigue, and improved cognitive and physical performance. Additionally, caffeine stimulates cyclic AMP (cAMP) levels by inhibiting phosphodiesterase (PDE), thereby amplifying cellular signaling involved in energy metabolism.
Caffeine also promotes lipolysis and thermogenesis by stimulating catecholamine release, making it a popular ingredient in metabolic and weight management formulations. Furthermore, its antioxidant activity contributes to cellular protection against oxidative stress.
Standardized Caffeine Extract is widely used in nutraceuticals, sports nutrition, functional beverages, and pharmaceuticals, offering consistent potency and targeted physiological effects. Dosage standardization ensures efficacy while minimizing the risk of overstimulation or side effects.
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