Boswellia Extract

Boswellia Extract – Anti-Inflammatory Phytocomplex Targeting Eicosanoid and Cytokine Pathways

Boswellia Extract, derived from the resin of Boswellia serrata, is a well-characterized botanical known for its potent anti-inflammatory, analgesic, and immunomodulatory properties. The extract is standardized primarily for boswellic acids, including acetyl-11-keto-β-boswellic acid (AKBA), a highly bioactive pentacyclic triterpenoid.

Biochemically, boswellic acids selectively inhibit 5-lipoxygenase (5-LOX), a key enzyme in leukotriene biosynthesis, thereby reducing pro-inflammatory eicosanoid production. Unlike conventional NSAIDs, Boswellia does not significantly affect cyclooxygenase (COX) activity, allowing for inflammation control with reduced gastrointestinal side effects.

Additionally, Boswellia modulates NF-κB signaling, leading to decreased expression of inflammatory mediators such as TNF-α, IL-1β, and IL-6. This positions Boswellia Extract as a valuable agent in managing chronic inflammatory conditions, including osteoarthritis, rheumatoid arthritis, asthma, and inflammatory bowel disease.

Produced using advanced extraction techniques to preserve the integrity and concentration of boswellic acids, Boswellia Extract is widely used in nutraceuticals, phytopharmaceuticals, and functional formulations targeting inflammation and joint health.